GPAT2

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GPAT2 mutation is significantly associated with the mutation status of many other genes, with 2,383 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPAT2-associated genes across cancer lineages are ANPEP, ZNF646, and MYRIP. Each is linked with GPAT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPAT2-to-partner and partner-to-GPAT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAT2→partner) and Y-score (partner→GPAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYANPEP →+3.632+3.930.003.00314
OVARYZNF646 →+3.217+3.684.006.00614
OVARYMYRIP →+3.217+3.684.006.00614
SKINADAMTS10 →+4.239+5.053.007.00713
SKINSTRIP1 →+5.824+5.824.002.00213
SKINTTC12 →+4.824+5.392.004.00413
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,383 associations by consensus.

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