Across TCGA cell cohorts, GPANK1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPANK1-associated genes across cancer lineages are CSN2, BPIFB6, and HSF5. Each is linked with GPANK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPANK1-to-partner and partner-to-GPANK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPANK1→partner) and Y-score (partner→GPANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CSN2 →	+0.031	+3.684	<.001	.006	3	1
LARGE_INTESTINE	BPIFB6 →	+0.020	+4.437	<.001	.004	3	1
LARGE_INTESTINE	HSF5 →	+0.035	+4.000	.004	.004	3	1
LARGE_INTESTINE	CASP12 →	+0.033	+3.684	<.001	.006	3	1
LARGE_INTESTINE	OR2J3 →	+0.044	+3.920	<.001	.005	3	1
LARGE_INTESTINE	OR2J1 →	+0.004	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

GPANK1 survival (RNA) · tumor vs normal (RNA) · all GPANK1 data types