GPALPP1

Across TCGA patient cohorts, GPALPP1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,885 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPALPP1-associated genes across cancer lineages are VPS36, NUFIP1, and MRPS31. Each is linked with GPALPP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GPALPP1-to-partner and partner-to-GPALPP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPALPP1 versus VPS36 in CCRCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPALPP1→partner) and Y-score (partner→GPALPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	VPS36 →	+0.422	+0.213	<.001	<.001	3	8
HNSC	NUFIP1 →	+0.608	+0.346	<.001	<.001	3	8
OV	MRPS31 →	+0.535	+0.563	<.001	<.001	3	7
HNSC	CLN5 →	+0.622	+0.372	<.001	<.001	3	7
LSCC	COG6 →	+0.494	+0.388	<.001	<.001	3	7
LSCC	PIBF1 →	+0.697	+0.393	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,885 associations by consensus.

GPALPP1 vs VPS36 — CCRCC

Explore this scatter interactively →