GP6

Across TCGA patient cohorts, GP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,122 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GP6-associated GO terms across cancer lineages are Protein dephosphorylation, Lysosomal transport, and Obsolete histone H3-K4 methylation. Each is linked with GP6 in more than 23 cancer types. Because this analysis shows association rather than direction, both GP6-to-partner and partner-to-GP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein dephosphorylation grouped by GP6-low versus GP6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GP6→partner) and Y-score (partner→GP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein dephosphorylation →	+0.054	+0.360	<.001	<.001	3	24
STAD	Lysosomal transport →	+0.060	+0.363	<.001	<.001	3	24
STAD	Obsolete histone H3-K4 methylation →	+0.060	+0.346	<.001	<.001	3	24
STAD	Vacuolar transport →	+0.061	+0.355	<.001	<.001	3	24
STAD	Response to endoplasmic reticulum stress →	+0.055	+0.360	<.001	<.001	3	24
STAD	Protein folding →	+0.054	+0.342	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,122 associations by consensus.

Protein dephosphorylation by GP6 expression — STAD

Explore this box plot interactively →