GP6

Across TCGA patient cohorts, GP6 protein abundance is significantly associated with the RNA expression of many other genes, with 4,617 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GP6-associated genes across cancer lineages are CXCR1, CXCR2, and C7. Each is linked with GP6 in more than 3 cancer types. Because this analysis shows association rather than direction, both GP6-to-partner and partner-to-GP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GP6 versus CXCR1 in GBM, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GP6→partner) and Y-score (partner→GP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CXCR1 →	+1.032	+0.645	<.001	<.001	3	4
GBM	CXCR2 →	+1.190	+0.827	<.001	.001	3	4
GBM	C7 →	+1.997	+0.762	<.001	<.001	3	4
BRCA	PTPRB →	+1.082	+1.291	<.001	<.001	3	4
LUAD	HBB →	+2.443	+0.594	<.001	.001	3	4
PDAC	LINC00924 →	+0.551	+0.745	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,617 associations by consensus.

GP6 vs CXCR1 — GBM

Explore this scatter interactively →