GP6

Across TCGA cell cohorts, GP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,563 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GP6-associated GO terms across cancer lineages are Pre-mRNA catabolic process, mRNA splice site recognition, and miRNA metabolic process. Each is linked with GP6 in more than 8 cancer types. Because this analysis shows association rather than direction, both GP6-to-partner and partner-to-GP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by GP6-low versus GP6-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GP6→partner) and Y-score (partner→GP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Pre-mRNA catabolic process →	+0.141	+0.320	.001	.003	3	9
OESOPHAGUS	mRNA splice site recognition →	+0.113	+0.325	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	miRNA metabolic process →	+0.087	+0.215	.007	.003	2	9
STOMACH	Viral transcription →	+0.127	+0.699	<.001	.007	3	7
OESOPHAGUS	mRNA catabolic process →	+0.062	+0.362	.004	.001	2	8
OESOPHAGUS	Endosomal transport →	+0.066	+0.379	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,563 associations by consensus.

Pre-mRNA catabolic process by GP6 expression — OESOPHAGUS

Explore this box plot interactively →