GP5

Across TCGA patient cohorts, GP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,161 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GP5-associated GO terms across cancer lineages are Regulation of Ras protein signal transduction, Nuclear-transcribed mRNA catabolic process, and Regulation of cell morphogenesis. Each is linked with GP5 in more than 27 cancer types. Because this analysis shows association rather than direction, both GP5-to-partner and partner-to-GP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Ras protein signal transduction grouped by GP5-low versus GP5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GP5→partner) and Y-score (partner→GP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of Ras protein signal transduction →	+0.058	+0.188	<.001	<.001	3	28
DLBC	Nuclear-transcribed mRNA catabolic process →	+0.069	+0.513	.002	<.001	3	27
STAD	Regulation of cell morphogenesis →	+0.058	+0.182	<.001	<.001	3	27
STAD	TOR signaling →	+0.059	+0.217	<.001	<.001	3	27
ESCA	Regulation of protein dephosphorylation →	+0.086	+0.209	<.001	<.001	3	27
ESCA	Positive regulation of protein dephosphorylation →	+0.072	+0.184	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,161 associations by consensus.

Regulation of Ras protein signal transduction by GP5 expression — STAD

Explore this box plot interactively →