GP5

Across TCGA patient cohorts, GP5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,916 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GP5-associated genes across cancer lineages are HBA1, HEMGN, and HBA2. Each is linked with GP5 in more than 4 cancer types. Because this analysis shows association rather than direction, both GP5-to-partner and partner-to-GP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GP5 versus HBA1 in PDAC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GP5→partner) and Y-score (partner→GP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HBA1 →	+1.979	+0.711	.002	.001	3	5
CCRCC	HEMGN →	+0.569	+0.372	.004	.007	3	5
CCRCC	HBA2 →	+1.843	+0.491	.004	.009	3	4
PDAC	HBB →	+2.825	+0.610	.001	.005	3	4
GBM	PPBP →	+1.667	+0.738	<.001	<.001	3	4
LSCC	CSF3 →	+1.452	+0.368	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,916 associations by consensus.

GP5 vs HBA1 — PDAC

Explore this scatter interactively →