GP5

Across TCGA cell cohorts, GP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,584 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GP5-associated GO terms across cancer lineages are Astral microtubule organization, Symbiont-mediated disruption of host cellular anatomical structure, and Symbiont-mediated disruption of host anatomical structure. Each is linked with GP5 in more than 9 cancer types. Because this analysis shows association rather than direction, both GP5-to-partner and partner-to-GP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Astral microtubule organization grouped by GP5-low versus GP5-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GP5→partner) and Y-score (partner→GP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Astral microtubule organization →	+0.085	+0.022	.003	<.001	3	10
STOMACH	Symbiont-mediated disruption of host cellular anatomical structure →	+0.102	+0.030	.004	.008	3	8
STOMACH	Symbiont-mediated disruption of host anatomical structure →	+0.102	+0.030	.004	.008	3	8
OVARY	MAPK cascade →	+0.044	+0.066	.001	.004	3	7
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.053	+0.618	.001	.001	3	7
SOFT_TISSUE	Negative regulation of calcium ion export across plasma membrane →	+0.073	+0.038	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,584 associations by consensus.

Astral microtubule organization by GP5 expression — SKIN

Explore this box plot interactively →