GP2

Across TCGA cell cohorts, GP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 192 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GP2-associated GO terms across cancer lineages are Calcium ion-regulated exocytosis of neurotransmitter, Semi-lunar valve development, and Positive regulation of cell-matrix adhesion. Each is linked with GP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GP2-to-partner and partner-to-GP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium ion-regulated exocytosis of neurotransmitter grouped by GP2-low versus GP2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GP2→partner) and Y-score (partner→GP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Calcium ion-regulated exocytosis of neurotransmitter →	+0.287	+1.045	<.001	.004	3	3
SKIN	Semi-lunar valve development →	-0.063	-0.106	<.001	.007	3	2
SKIN	Positive regulation of cell-matrix adhesion →	-0.085	-0.111	.001	.008	3	2
SKIN	Myelination in peripheral nervous system →	-0.097	-0.074	<.001	.009	3	2
LUNG_SCLC	Regulation of lymphocyte chemotaxis →	-0.090	-0.695	.002	.008	3	2
LUNG_SCLC	Inhibitory postsynaptic potential →	+0.711	+1.073	.008	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 192 associations by consensus.

Calcium ion-regulated exocytosis of neurotransmitter by GP2 expression — LUNG_SCLC

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