GOT1L1

Across TCGA cell cohorts, GOT1L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 201 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GOT1L1-associated GO terms across cancer lineages are Negative regulation of calcium ion transport into cytosol, Telomere maintenance via telomere lengthening, and Peripheral nervous system axon regeneration. Each is linked with GOT1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOT1L1-to-partner and partner-to-GOT1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion transport into cytosol grouped by GOT1L1-low versus GOT1L1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GOT1L1→partner) and Y-score (partner→GOT1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of calcium ion transport into cytosol →	-0.165	-0.129	<.001	.009	3	1
BONE	Telomere maintenance via telomere lengthening →	+0.109	+0.127	<.001	.009	3	1
BONE	Peripheral nervous system axon regeneration →	-0.329	-0.162	<.001	.004	3	1
BONE	Neural crest formation →	+0.179	+0.162	<.001	.004	3	1
BONE	Peptidyl-glutamate ADP-deribosylation →	+0.166	+0.162	<.001	.004	3	1
BONE	Secondary piRNA processing →	+0.438	+0.158	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 201 associations by consensus.

Negative regulation of calcium ion transport into cytosol by GOT1L1 expression — BONE

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