GOT1L1

Across TCGA pan-cancer cohorts, GOT1L1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of GOT1L1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where GOT1L1 RNA is repressed in tumor relative to normal tissue. In most cancer types GOT1L1 is over-expressed in tumor, although a few such as BLCA show the opposite, repressed pattern.

BLCA and THCA are the cancer types where GOT1L1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GOT1L1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	−0.155	.007	11	view →
THCA	All	All	+0.011	.002	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

GOT1L1–BLCA

Open the BLCA breakdown →