GOT1L1

Across TCGA cell cohorts, GOT1L1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GOT1L1-associated genes across cancer lineages are OR10J5, KRTAP6-1, and PM20D1. Each is linked with GOT1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOT1L1-to-partner and partner-to-GOT1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10J5 grouped by GOT1L1-low versus GOT1L1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOT1L1→partner) and Y-score (partner→GOT1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR10J5 →	+0.011	+3.700	<.001	.009	3	1
SKIN	KRTAP6-1 →	+0.042	+3.700	<.001	.009	3	1
SKIN	PM20D1 →	+0.151	+2.943	<.001	.006	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR10J5 by GOT1L1 expression — SKIN

Explore this box plot interactively →