GOSR2

Across TCGA patient cohorts, GOSR2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,544 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GOSR2-associated genes across cancer lineages are ELOVL2, ELOVL2-AS1, and LINC02139. Each is linked with GOSR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOSR2-to-partner and partner-to-GOSR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GOSR2 versus ELOVL2 in GBM, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOSR2→partner) and Y-score (partner→GOSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ELOVL2 →	+1.994	+0.405	.001	.009	3	2
GBM	ELOVL2-AS1 →	+0.989	+0.321	.003	.005	3	2
BRCA	LINC02139 →	+0.240	+1.582	<.001	.008	3	2
LSCC	CDS2 →	+0.483	+0.342	<.001	.001	3	1
LSCC	EEF1AKNMT →	+0.606	+0.316	.003	.002	3	1
LSCC	ATP11C →	+0.701	+0.408	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,544 associations by consensus.

GOSR2 vs ELOVL2 — GBM

Explore this scatter interactively →