GOSR2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOSR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,395 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GOSR2-associated GO terms across cancer lineages are Endoplasmic reticulum to cytosol transport, Retrograde protein transport, ER to cytosol, and Golgi transport vesicle coating. Each is linked with GOSR2 in more than 15 cancer types. Because this analysis shows association rather than direction, both GOSR2-to-partner and partner-to-GOSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to cytosol transport grouped by GOSR2-low versus GOSR2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GOSR2→partner) and Y-score (partner→GOSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEEndoplasmic reticulum to cytosol transport →+0.120+0.706<.001<.001316
SOFT_TISSUERetrograde protein transport, ER to cytosol →+0.120+0.706<.001<.001316
KIDNEYGolgi transport vesicle coating →+0.104+0.471.007.009315
KIDNEYCOPI coating of Golgi vesicle →+0.104+0.471.007.009315
STOMACHEstablishment of protein localization to membrane →+0.072+0.915<.001.002315
KIDNEYCOPI-coated vesicle budding →+0.104+0.471.007.009315
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,395 associations by consensus.

Endoplasmic reticulum to cytosol transport by GOSR2 expression — SOFT_TISSUE

Box plot of Endoplasmic reticulum to cytosol transport in GOSR2-low vs GOSR2-high samples in SOFT_TISSUE.

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Exploration