GORAB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GORAB protein abundance is significantly associated with the RNA expression of many other genes, with 8,187 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GORAB-associated genes across cancer lineages are EEF1AKNMT, COP1, and RAB3GAP2. Each is linked with GORAB in more than 5 cancer types. Because this analysis shows association rather than direction, both GORAB-to-partner and partner-to-GORAB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GORAB versus EEF1AKNMT in UCEC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GORAB→partner) and Y-score (partner→GORAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEEF1AKNMT →+0.632+0.451.007.00236
UCECCOP1 →+0.500+0.547<.001<.00136
UCECRAB3GAP2 →+0.688+0.591<.001<.00135
UCECPIGC →+0.615+0.595<.001<.00135
UCECUBE2Q1 →+0.614+0.483<.001.00135
UCECKIFAP3 →+0.796+0.667<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,187 associations by consensus.

GORAB vs EEF1AKNMT — UCEC

Per-sample scatter of GORAB vs EEF1AKNMT in UCEC (Pearson r = 0.29).

Explore this scatter interactively →

Exploration