GORAB

Across TCGA cell cohorts, GORAB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,670 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GORAB-associated GO terms across cancer lineages are Centrosome cycle, Protein localization to vacuole, and Regulation of alternative mRNA splicing, via spliceosome. Each is linked with GORAB in more than 13 cancer types. Because this analysis shows association rather than direction, both GORAB-to-partner and partner-to-GORAB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome cycle grouped by GORAB-low versus GORAB-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GORAB→partner) and Y-score (partner→GORAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Centrosome cycle →	+0.083	+0.956	<.001	<.001	3	14
LUNG_SCLC	Protein localization to vacuole →	+0.067	+0.966	.005	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.109	+0.782	<.001	<.001	3	13
SOFT_TISSUE	Response to UV →	+0.044	+0.519	.001	.006	3	13
OVARY	Establishment of protein localization to organelle →	+0.048	+0.968	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of chromatin organization →	+0.145	+0.899	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,670 associations by consensus.

Centrosome cycle by GORAB expression — OVARY

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