GORAB-AS1

Across TCGA pan-cancer cohorts, GORAB-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated GORAB-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher GORAB-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GORAB-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

KIRC, KIRP, and UCS are the cancer types where GORAB-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.552	0.693	<.001	121	view →
KIRP	DFS	Median	All	0.345	0.753	<.001	100	view →
UCS	OS	Tertile	II,III,IV	0.773	0.311	.001	86	view →
UCEC	OS	Median	III,IV	0.433	0.718	.004	46	view →
LIHC	OS	Median	III,IV	0.329	0.660	<.001	26	view →
ACC	DFS	Median	All	0.423	0.720	.002	26	view →
BLCA	DFS	Quartile	All	0.430	0.715	.003	24	view →
KICH	OS	Tertile	II,III,IV	0.201	1.000	<.001	23	view →
BRCA	OS	Quartile	All	0.895	0.951	.009	20	view →
THCA	DFS	Median	III,IV	0.767	0.945	.003	20	view →
SKCM	DFS	Median	IV	0.593	0.149	.011	19	view →
UVM	DFS	Median	All	0.278	0.672	.005	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

GORAB-AS1–KIRC (OS)

Open the KIRC breakdown →