GON4L

Across TCGA patient cohorts, GON4L RNA expression is significantly associated with the protein abundance of many other proteins, with 15,371 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GON4L-associated proteins across cancer lineages are DHX9, GATAD2B, and POGZ. Each is linked with GON4L in more than 7 cancer types. Because this analysis shows association rather than direction, both GON4L-to-partner and partner-to-GON4L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GON4L versus DHX9 in LSCC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GON4L→partner) and Y-score (partner→GON4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DHX9 →	+0.247	+0.442	<.001	<.001	3	8
GBM	GATAD2B →	+0.312	+0.267	<.001	<.001	3	8
GBM	POGZ →	+0.355	+0.422	<.001	<.001	3	7
GBM	HDGF →	+0.344	+0.274	<.001	<.001	3	7
LSCC	RPRD2 →	+0.316	+0.471	<.001	<.001	3	7
HNSC	RBBP5 →	+0.255	+0.681	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,371 associations by consensus.

GON4L vs DHX9 — LSCC

Explore this scatter interactively →