GON4L

Across TCGA patient cohorts, GON4L protein abundance is significantly associated with the protein abundance of many other proteins, with 17,584 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GON4L-associated proteins across cancer lineages are NDUFC2, DOT1L, and CSTF2. Each is linked with GON4L in more than 4 cancer types. Because this analysis shows association rather than direction, both GON4L-to-partner and partner-to-GON4L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GON4L versus NDUFC2 in GBM, with a Pearson correlation of -0.42.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GON4L→partner) and Y-score (partner→GON4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NDUFC2 →	-0.466	-0.490	<.001	<.001	3	5
OV	DOT1L →	+2.352	+3.039	<.001	<.001	3	5
LSCC	CSTF2 →	+0.261	+0.307	<.001	<.001	3	5
BRCA	MORC2_S725 →	+1.573	+0.430	<.001	<.001	3	5
GBM	BPTF →	+0.258	+0.428	<.001	<.001	3	4
LSCC	CCNK →	+0.271	+0.335	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,584 associations by consensus.

GON4L vs NDUFC2 — GBM

Explore this scatter interactively →