GOLT1B

Across TCGA pan-cancer cohorts, GOLT1B mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GOLT1B data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GOLT1B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated GOLT1B expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, LUAD, and LSCC are the cancer types where GOLT1B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	1.000	0.602	.011	20	view →
LUAD	DFS	Median	III,IV	0.526	0.952	.003	17	view →
LSCC	OS	Tertile	II,III,IV	0.741	1.000	.024	3	view →
HNSC	DFS	Quartile	All	0.756	0.516	.021	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GOLT1B–UCEC (OS)

Open the UCEC breakdown →