GOLT1B

Across TCGA patient cohorts, GOLT1B mutation is significantly associated with the RNA expression of many other genes, with 1,072 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLT1B-associated genes across cancer lineages are MIR4510, RNU4-84P, and MIR3135A. Each is linked with GOLT1B in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLT1B-to-partner and partner-to-GOLT1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4510 grouped by GOLT1B-low versus GOLT1B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLT1B→partner) and Y-score (partner→GOLT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4510 →	+0.400	+6.342	<.001	.001	3	2
LUSC	RNU4-84P →	+0.218	+6.327	<.001	<.001	3	2
UCEC	MIR3135A →	+0.405	+2.316	<.001	.007	3	2
UCEC	RN7SL97P →	+0.230	+3.199	<.001	<.001	3	2
SKCM	IQCF1 →	+0.127	+3.972	.001	.006	3	1
SKCM	ACTL9 →	+0.036	+3.953	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,072 associations by consensus.

MIR4510 by GOLT1B expression — CESC

Explore this box plot interactively →