GOLT1A

Across TCGA pan-cancer cohorts, GOLT1A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GOLT1A data layer compared with 20 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher GOLT1A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GOLT1A expression acts as an unfavorable survival marker.

ESCA, STAD, and BRCA are the cancer types where GOLT1A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.117	0.703	<.001	36	view →
STAD	OS	Median	All	0.184	0.730	.001	33	view →
BRCA	DFS	Median	All	0.433	0.903	.001	22	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

GOLT1A–ESCA (OS)

Open the ESCA breakdown →