GOLIM4

Across TCGA patient cohorts, GOLIM4 mutation is significantly associated with the RNA expression of many other genes, with 2,562 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLIM4-associated genes across cancer lineages are LINC02506, AMDHD2, and RNU6-548P. Each is linked with GOLIM4 in more than 3 cancer types. Because this analysis shows association rather than direction, both GOLIM4-to-partner and partner-to-GOLIM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02506 grouped by GOLIM4-low versus GOLIM4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLIM4→partner) and Y-score (partner→GOLIM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02506 →	+1.077	+2.109	<.001	<.001	3	4
UCEC	AMDHD2 →	+0.550	+2.895	<.001	<.001	3	3
SKCM	RNU6-548P →	+0.611	+3.341	.008	.005	3	3
UCEC	EI24 →	+0.410	+3.000	.005	.001	3	2
UCEC	NOCT →	+0.586	+2.403	<.001	<.001	3	2
UCEC	SLC25A4 →	+0.451	+1.673	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,562 associations by consensus.

LINC02506 by GOLIM4 expression — UCEC

Explore this box plot interactively →