GOLGA8S

Across TCGA cell cohorts, GOLGA8S mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA8S-associated genes across cancer lineages are OPN4, C3orf22, and TMEM212. Each is linked with GOLGA8S in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8S-to-partner and partner-to-GOLGA8S results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN4 grouped by GOLGA8S-low versus GOLGA8S-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8S→partner) and Y-score (partner→GOLGA8S) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OPN4 →	+0.057	+5.121	<.001	<.001	3	1
BLOOD_Leukemia	C3orf22 →	+0.080	+3.716	<.001	.009	3	1
BLOOD_Leukemia	TMEM212 →	+1.131	+4.567	<.001	.001	3	1
BLOOD_Leukemia	SPANXN5 →	+0.011	+4.384	<.001	.006	3	1
BLOOD_Leukemia	CDRT15L2 →	+0.218	+4.691	.002	<.001	3	1
BLOOD_Leukemia	ARSF →	+0.263	+3.705	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OPN4 by GOLGA8S expression — BLOOD_Leukemia

Explore this box plot interactively →