GOLGA8S

Across TCGA pan-cancer cohorts, GOLGA8S RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated GOLGA8S data layer compared with 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher GOLGA8S RNA is associated with better overall survival. In most high-consensus cancer types, elevated GOLGA8S expression acts as an unfavorable survival marker, although some lineages such as LUAD and MESO show a favorable association.

LUAD, MESO, and PAAD are the cancer types where GOLGA8S RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.653	0.438	<.001	56	view →
MESO	OS	Tertile	All	0.573	0.300	<.001	43	view →
PAAD	DFS	Median	All	0.512	0.262	<.001	37	view →
UVM	OS	Tertile	III,IV	0.239	0.870	.004	31	view →
LUSC	DFS	Tertile	II,III,IV	0.625	0.803	.005	27	view →
KIRC	DFS	Median	III,IV	0.545	0.736	<.001	25	view →
ESCA	DFS	Median	III,IV	0.506	0.251	.015	18	view →
THYM	DFS	Tertile	III,IV	0.875	0.481	.015	9	view →
READ	OS	Median	III,IV	0.667	0.299	.011	8	view →
UCEC	DFS	Median	All	0.801	0.861	.033	8	view →
LIHC	OS	Tertile	III,IV	0.756	0.540	.018	5	view →
ACC	OS	Tertile	III,IV	0.508	0.801	.043	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

GOLGA8S–LUAD (OS)

Open the LUAD breakdown →