GOLGA8Q

Across TCGA cell cohorts, GOLGA8Q mutation is significantly associated with the RNA expression of many other genes, with 163 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA8Q-associated genes across cancer lineages are ZNF106, TGM5, and NDRG1. Each is linked with GOLGA8Q in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8Q-to-partner and partner-to-GOLGA8Q results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF106 grouped by GOLGA8Q-low versus GOLGA8Q-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8Q→partner) and Y-score (partner→GOLGA8Q) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZNF106 →	+0.657	+3.214	.004	.006	3	1
BLOOD_Leukemia	TGM5 →	+2.038	+3.199	<.001	.007	3	1
BLOOD_Leukemia	NDRG1 →	+1.757	+3.199	.008	.007	3	1
BLOOD_Leukemia	DUSP3 →	+1.595	+3.199	<.001	.007	3	1
BLOOD_Leukemia	SLC26A8 →	+1.020	+3.309	<.001	.009	3	1
BLOOD_Leukemia	RNF8 →	+0.649	+3.199	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 163 associations by consensus.

ZNF106 by GOLGA8Q expression — BLOOD_Leukemia

Explore this box plot interactively →