GOLGA8Q

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, GOLGA8Q RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of GOLGA8Q’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where GOLGA8Q RNA is repressed in tumor relative to normal tissue. In most cancer types GOLGA8Q is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, BRCA, and LUSC are the cancer types where GOLGA8Q tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GOLGA8Q RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAMaleIII,IV−1.860<.00111view →
BRCAAllIII,IV−0.114<.0016view →
LUSCMaleAll−0.063<.0013view →
READAllII,III,IV−0.110.0401view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

GOLGA8Q–THCA

Tumor-vs-normal expression box plot for GOLGA8Q RNA in THCA.

Open the THCA breakdown →

Exploration