GOLGA8N

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA8N mutation is significantly associated with the mutation status of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA8N-associated genes across cancer lineages are CEBPA, GOLGA8H, and GOLGA8R. Each is linked with GOLGA8N in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8N-to-partner and partner-to-GOLGA8N results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CEBPA grouped by GOLGA8N-low versus GOLGA8N-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8N→partner) and Y-score (partner→GOLGA8N) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaCEBPA →+4.430+3.823.001.00111
BLOOD_LeukemiaGOLGA8H →+3.845+3.548.003.00311
BLOOD_LeukemiaGOLGA8R →+1.997+2.857.005.00511
BLOOD_LeukemiaGOLGA8O →+5.167+4.787<.001<.00111
BLOOD_LeukemiaPCM1 →+2.523+2.960.005.00511
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CEBPA by GOLGA8N expression — BLOOD_Leukemia

Box plot of CEBPA in GOLGA8N-low vs GOLGA8N-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration