Q-omics provides the consensus-scored GOLGA8R profile across patient tissues and cancer cell-line models. GOLGA8R expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in LGG. Among the 18 cancer types available for tumor–normal comparison, GOLGA8R is differentially expressed in 12, with the highest sampling consensus in THCA. Additionally, GOLGA8R RNA expression shows 19,332 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight LGG, THCA, and THYM as cancer lineages where GOLGA8R shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GOLGA8R — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GOLGA8R survival associations across molecular data types. GOLGA8R RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GOLGA8R RNA expression–survival associations across cancer types. High GOLGA8R expression shows unfavorable associations in LGG, LUSC, CESC and READ, but favorable associations in HNSC and KIRP. The LGG Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LGG as the clearest survival context for GOLGA8R RNA expression.
This table summarizes GOLGA8R tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for GOLGA8R. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GOLGA8R shows lower tumor expression in THCA, BLCA, BRCA, UCEC, LUSC and COAD. The THCA box plot shows higher GOLGA8R RNA expression in normal versus tumor tissue (log2 FC = −1.258, t-test p < 0.001).
This table shows molecular features associated with GOLGA8R in patient tissues and cancer cell lines. In patient samples, GOLGA8R shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, GOLGA8R RNA and mutation anchors are most strongly linked to RNA-expression features, especially in PANCREAS, while CRISPR and shRNA rows add functional-dependency signals in LARGE_INTESTINE and CNS.
