GOLGA8K

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA8K RNA expression is significantly associated with the go_rna of many other GO terms, with 3,828 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA8K-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Negative regulation of myoblast fusion. Each is linked with GOLGA8K in more than 13 cancer types. Because this analysis shows association rather than direction, both GOLGA8K-to-partner and partner-to-GOLGA8K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by GOLGA8K-low versus GOLGA8K-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8K→partner) and Y-score (partner→GOLGA8K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTNegative regulation of syncytium formation by plasma membrane fusion →+0.169+0.300<.001<.001314
UPPER_AERODIGESTIVE_TRACTPositive regulation of intracellular steroid hormone receptor signaling pathway →+0.150+0.200<.001<.001314
UPPER_AERODIGESTIVE_TRACTNegative regulation of myoblast fusion →+0.171+0.274<.001<.001313
STOMACHMicrotubule polymerization or depolymerization →+0.084+0.256<.001.006313
UPPER_AERODIGESTIVE_TRACTRegulation of telomere maintenance →+0.063+0.280<.001<.001313
BONEViral translational termination-reinitiation →+0.084+0.781<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,828 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by GOLGA8K expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Negative regulation of syncytium formation by plasma membrane fusion in GOLGA8K-low vs GOLGA8K-high samples in UPPER_AERODIGESTIVE_TRACT.

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