GOLGA8K

Across TCGA pan-cancer cohorts, GOLGA8K RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated GOLGA8K data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GOLGA8K RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GOLGA8K expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

UCEC, LUSC, and COAD are the cancer types where GOLGA8K RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	II,III,IV	0.593	0.793	<.001	108	view →
LUSC	DFS	Median	III,IV	0.479	0.781	<.001	89	view →
COAD	DFS	Median	All	0.714	0.821	<.001	69	view →
HNSC	DFS	Median	IV	0.646	0.317	.001	49	view →
BLCA	DFS	Quartile	IV	0.177	0.370	.003	32	view →
SKCM	DFS	Quartile	III,IV	0.624	0.307	.001	32	view →
ACC	OS	Quartile	III,IV	0.716	0.329	.008	29	view →
ESCA	OS	Tertile	IV	0.095	0.575	.045	24	view →
MESO	OS	Tertile	All	0.560	0.293	.001	17	view →
KIRP	DFS	Quartile	All	1.000	0.608	.004	15	view →
KICH	DFS	Tertile	II,III,IV	0.365	0.899	.019	14	view →
OV	OS	Quartile	IV	0.871	0.529	.006	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

GOLGA8K–UCEC (DFS)

Open the UCEC breakdown →