GOLGA8K

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA8K mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA8K-associated genes across cancer lineages are SLC6A7, TCF23, and MRAP. Each is linked with GOLGA8K in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8K-to-partner and partner-to-GOLGA8K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC6A7 grouped by GOLGA8K-low versus GOLGA8K-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8K→partner) and Y-score (partner→GOLGA8K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaSLC6A7 →+0.015+4.824.006<.00131
BLOOD_LeukemiaTCF23 →+0.783+3.855.001.00731
BLOOD_LeukemiaMRAP →+0.085+4.567<.001.00131
BLOOD_LeukemiaCD300H →+0.416+4.234<.001.00331
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SLC6A7 by GOLGA8K expression — BLOOD_Leukemia

Box plot of SLC6A7 in GOLGA8K-low vs GOLGA8K-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration