GOLGA6L6

Across TCGA patient cohorts, GOLGA6L6 mutation is significantly associated with the RNA expression of many other genes, with 390 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA6L6-associated genes across cancer lineages are MIR6075, RPS3AP17, and RPL17P45. Each is linked with GOLGA6L6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6L6-to-partner and partner-to-GOLGA6L6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6075 grouped by GOLGA6L6-low versus GOLGA6L6-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6L6→partner) and Y-score (partner→GOLGA6L6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6075 →	+0.257	+2.718	.008	.004	3	2
CESC	RPS3AP17 →	+0.059	+5.812	<.001	.003	3	2
CESC	RPL17P45 →	+0.093	+5.669	<.001	.003	3	2
CESC	RNA5SP531 →	+0.525	+5.969	<.001	.002	3	2
UCEC	RNU1-133P →	+0.087	+3.111	<.001	.004	3	2
UCEC	RNU6-497P →	+0.174	+2.288	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 390 associations by consensus.

MIR6075 by GOLGA6L6 expression — BRCA

Explore this box plot interactively →