GOLGA6L6

Across TCGA patient cohorts, GOLGA6L6 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA6L6-associated genes across cancer lineages are FoxM1, GSK-3_pS9, and MEK1. Each is linked with GOLGA6L6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6L6-to-partner and partner-to-GOLGA6L6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by GOLGA6L6-low versus GOLGA6L6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6L6→partner) and Y-score (partner→GOLGA6L6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.305	+2.000	.002	.010	3	1
UCEC	GSK-3_pS9 →	-0.332	-1.584	.036	.036	3	1
UCEC	MEK1 →	+0.420	+3.584	.003	.002	3	1
UCEC	Notch1 →	+0.131	+1.594	.018	.042	3	1
UCEC	PDCD4 →	-0.523	-2.584	.004	.010	3	1
UCEC	Smad1 →	+0.153	+2.000	.012	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

FoxM1 by GOLGA6L6 expression — UCEC

Explore this box plot interactively →