GOLGA6L3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA6L3 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA6L3-associated genes across cancer lineages are CA15P2, RN7SL248P, and SNORD116-5. Each is linked with GOLGA6L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6L3-to-partner and partner-to-GOLGA6L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6L3→partner) and Y-score (partner→GOLGA6L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCA15P2 →+0.185+5.031<.001.00931
UCECRN7SL248P →+0.296+6.722<.001<.00131
UCECSNORD116-5 →+0.763+6.123<.001.00231
UCECMIR526B →+1.062+5.186<.001.00731
UCECMIR525 →+0.806+4.982.001.00931
UCECMIR204 →+0.622+5.694<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

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