GOLGA6L1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA6L1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible GOLGA6L1-associated genes across cancer lineages are OR6Q1, KLHL40, and RBMY1J. Each is linked with GOLGA6L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6L1-to-partner and partner-to-GOLGA6L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6Q1 grouped by GOLGA6L1-low versus GOLGA6L1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6L1→partner) and Y-score (partner→GOLGA6L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR6Q1 →+0.030+6.022<.001.00131
OVARYKLHL40 →+0.011+4.450<.001.00431
OVARYRBMY1J →+0.017+4.807<.001.00331
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR6Q1 by GOLGA6L1 expression — LARGE_INTESTINE

Box plot of OR6Q1 in GOLGA6L1-low vs GOLGA6L1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration