Across TCGA pan-cancer cohorts, GOLGA6B RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated GOLGA6B data layer compared with 2 for mutation status.
The strongest signal is observed in uveal melanoma (UVM), where higher GOLGA6B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GOLGA6B expression acts as an unfavorable survival marker, although some lineages such as SCLC and CHOL show a favorable association.
UVM, UCS, and THCA are the cancer types where GOLGA6B RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.