GOLGA1

Across TCGA cell cohorts, GOLGA1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA1-associated genes across cancer lineages are OR4E1, GML, and PTH. Each is linked with GOLGA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA1-to-partner and partner-to-GOLGA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4E1 grouped by GOLGA1-low versus GOLGA1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA1→partner) and Y-score (partner→GOLGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR4E1 →	+0.150	+5.781	<.001	.001	3	2
BLOOD_Leukemia	GML →	+0.080	+4.152	<.001	.009	3	2
BLOOD_Lymphoma	PTH →	+0.023	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	OR52K2 →	+0.012	+5.209	<.001	.005	3	1
STOMACH	KRTAP4-2 →	+0.109	+5.285	<.001	.003	3	1
BREAST	OR1L3 →	+0.022	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

OR4E1 by GOLGA1 expression — BREAST

Explore this box plot interactively →