GNRHR

Across TCGA patient cohorts, GNRHR RNA expression is significantly associated with the RNA expression of many other genes, with 19,077 significant associations in total. UVM shows the largest number of these associations.

The most reproducible GNRHR-associated genes across cancer lineages are LIN54, RUFY3, and ANKRD17. Each is linked with GNRHR in more than 30 cancer types. Because this analysis shows association rather than direction, both GNRHR-to-partner and partner-to-GNRHR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNRHR versus LIN54 in UVM, with a Pearson correlation of 0.68.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNRHR→partner) and Y-score (partner→GNRHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	LIN54 →	+1.138	+0.137	<.001	<.001	3	31
UVM	RUFY3 →	+1.170	+0.116	<.001	<.001	3	31
DLBC	ANKRD17 →	+1.100	+0.196	<.001	<.001	3	30
UVM	APC →	+1.061	+0.118	<.001	<.001	3	30
UVM	DMXL1 →	+1.626	+0.134	<.001	<.001	3	30
DLBC	ZDHHC21 →	+1.200	+0.214	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,077 associations by consensus.

GNRHR vs LIN54 — UVM

Explore this scatter interactively →