GNRHR

Across TCGA patient cohorts, GNRHR RNA expression is significantly associated with the protein abundance of many other proteins, with 7,563 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNRHR-associated proteins across cancer lineages are METTL1, REEP1, and RPL7. Each is linked with GNRHR in more than 2 cancer types. Because this analysis shows association rather than direction, both GNRHR-to-partner and partner-to-GNRHR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNRHR versus METTL1 in UCEC, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNRHR→partner) and Y-score (partner→GNRHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	METTL1 →	-0.341	-0.812	.001	<.001	3	3
COAD	REEP1 →	+1.309	+0.199	<.001	<.001	3	3
GBM	RPL7 →	-0.326	-0.510	<.001	.001	3	3
BRCA	MLPH_S510 →	+0.792	+0.142	<.001	.008	3	3
BRCA	PTN →	+0.799	+0.249	.001	<.001	3	2
UCEC	ARID4B →	+0.119	+0.523	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,563 associations by consensus.

GNRHR vs METTL1 — UCEC

Explore this scatter interactively →