GNRH2

Across TCGA patient cohorts, GNRH2 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GNRH2-associated genes across cancer lineages are RNU6-918P, RN7SL392P, and FGF7P1. Each is linked with GNRH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GNRH2-to-partner and partner-to-GNRH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-918P grouped by GNRH2-low versus GNRH2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNRH2→partner) and Y-score (partner→GNRH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-918P →	+1.510	+5.420	<.001	.005	3	2
UCEC	RN7SL392P →	+0.606	+4.982	<.001	.009	3	2
BLCA	FGF7P1 →	+0.189	+7.640	<.001	.009	3	1
CESC	MED28P2 →	+0.167	+6.837	<.001	<.001	3	1
CESC	OR52H2P →	+0.083	+5.669	<.001	.003	3	1
CESC	RNU6-150P →	+0.427	+5.103	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

RNU6-918P by GNRH2 expression — UCEC

Explore this box plot interactively →