GNPTAB

Across TCGA patient cohorts, GNPTAB RNA expression is significantly associated with the protein abundance of many other proteins, with 12,352 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GNPTAB-associated proteins across cancer lineages are SCYL2, SERPINB8, and RAP1GAP2_S558. Each is linked with GNPTAB in more than 3 cancer types. Because this analysis shows association rather than direction, both GNPTAB-to-partner and partner-to-GNPTAB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNPTAB versus SCYL2 in UCEC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNPTAB→partner) and Y-score (partner→GNPTAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SCYL2 →	+0.182	+0.498	<.001	<.001	3	4
BRCA	SERPINB8 →	+0.544	+0.524	<.001	<.001	3	4
CCRCC	RAP1GAP2_S558 →	-1.103	-0.426	.009	.007	3	4
LUAD	RPL3 →	-0.290	-0.328	.003	.001	3	3
LSCC	TFG →	-0.215	-0.357	.005	.003	3	3
BRCA	CIC_S173 →	+0.421	+0.626	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,352 associations by consensus.

GNPTAB vs SCYL2 — UCEC

Explore this scatter interactively →