GNPTAB

Across TCGA cell cohorts, GNPTAB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,497 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GNPTAB-associated GO terms across cancer lineages are Vacuolar transport, Protein localization to lysosome, and Protein targeting to vacuole. Each is linked with GNPTAB in more than 14 cancer types. Because this analysis shows association rather than direction, both GNPTAB-to-partner and partner-to-GNPTAB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transport grouped by GNPTAB-low versus GNPTAB-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNPTAB→partner) and Y-score (partner→GNPTAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Vacuolar transport →	+0.063	+0.981	.001	.006	3	15
OESOPHAGUS	Protein localization to lysosome →	+0.099	+0.940	.002	<.001	3	14
OESOPHAGUS	Protein targeting to vacuole →	+0.104	+0.833	.007	<.001	3	14
OESOPHAGUS	Protein localization to vacuole →	+0.084	+0.961	.008	<.001	2	15
BONE	Establishment of protein localization to vacuole →	+0.086	+1.374	<.001	<.001	3	14
OESOPHAGUS	Protein targeting to lysosome →	+0.118	+1.006	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,497 associations by consensus.

Vacuolar transport by GNPTAB expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →