GNPNAT1

Across TCGA patient cohorts, GNPNAT1 mutation is significantly associated with the RNA expression of many other genes, with 445 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GNPNAT1-associated genes across cancer lineages are PRR23D3P, TCERG1P2, and PMM2P1. Each is linked with GNPNAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GNPNAT1-to-partner and partner-to-GNPNAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR23D3P grouped by GNPNAT1-low versus GNPNAT1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNPNAT1→partner) and Y-score (partner→GNPNAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	PRR23D3P →	+0.090	+6.147	<.001	.002	3	1
BLCA	TCERG1P2 →	+0.098	+5.038	.003	.009	3	1
BLCA	PMM2P1 →	+0.104	+6.289	<.001	.001	3	1
BRCA	PRR20A →	+0.024	+8.471	<.001	.005	3	1
UCEC	RN7SL592P →	+0.153	+2.123	.007	.009	3	1
UCEC	MIR4710 →	+0.522	+2.709	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 445 associations by consensus.

PRR23D3P by GNPNAT1 expression — BLCA

Explore this box plot interactively →