GNPDA1

Across TCGA cell cohorts, GNPDA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,157 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GNPDA1-associated GO terms across cancer lineages are Pigment granule organization, Melanosome organization, and Endosomal lumen acidification. Each is linked with GNPDA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both GNPDA1-to-partner and partner-to-GNPDA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pigment granule organization grouped by GNPDA1-low versus GNPDA1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNPDA1→partner) and Y-score (partner→GNPDA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Pigment granule organization →	+0.098	+0.633	<.001	<.001	3	10
SKIN	Melanosome organization →	+0.098	+0.633	<.001	<.001	3	10
KIDNEY	Endosomal lumen acidification →	+0.112	+0.659	.002	<.001	3	10
BONE	Synaptic vesicle lumen acidification →	+0.150	+0.883	<.001	<.001	3	9
BREAST	Regulation of insulin secretion →	-0.047	-0.574	.006	.003	3	9
BLOOD_Myeloma	N-acetylglucosamine catabolic process →	+0.133	+1.326	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,157 associations by consensus.

Pigment granule organization by GNPDA1 expression — SKIN

Explore this box plot interactively →