Across TCGA pan-cancer cohorts, GNPATP RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of GNPATP’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where GNPATP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GNPATP is over-expressed in tumor.
COAD and KICH are the cancer types where GNPATP tumor–normal differential expression is most reproducible.