GNMT

Across TCGA patient cohorts, GNMT RNA expression is significantly associated with the protein abundance of many other proteins, with 18,389 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GNMT-associated proteins across cancer lineages are RPS6KA5, ARFGEF3, and NFIA. Each is linked with GNMT in more than 4 cancer types. Because this analysis shows association rather than direction, both GNMT-to-partner and partner-to-GNMT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNMT versus RPS6KA5 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNMT→partner) and Y-score (partner→GNMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPS6KA5 →	+0.534	+1.241	<.001	.001	3	5
BRCA	ARFGEF3 →	+0.640	+1.422	<.001	<.001	3	5
BRCA	NFIA →	+0.492	+0.938	<.001	<.001	3	5
HNSC	DDAH1 →	+0.659	+0.648	<.001	<.001	3	5
BRCA	JUNB →	-0.432	-1.121	<.001	<.001	3	5
BRCA	TMX4 →	+0.420	+0.691	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,389 associations by consensus.

GNMT vs RPS6KA5 — BRCA

Explore this scatter interactively →