GNLY

Across TCGA patient cohorts, GNLY RNA expression is significantly associated with the protein abundance of many other proteins, with 14,905 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNLY-associated proteins across cancer lineages are TYMP, PSMB6, and SKAP2. Each is linked with GNLY in more than 8 cancer types. Because this analysis shows association rather than direction, both GNLY-to-partner and partner-to-GNLY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNLY versus TYMP in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNLY→partner) and Y-score (partner→GNLY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TYMP →	+0.656	+0.804	<.001	<.001	3	9
LUAD	PSMB6 →	-0.444	-0.998	<.001	<.001	3	9
UCEC	SKAP2 →	+0.749	+1.070	<.001	.002	3	9
HNSC	GBP1 →	+0.958	+1.285	<.001	<.001	3	9
BRCA	ITGAL →	+0.660	+1.162	<.001	<.001	3	9
BRCA	STAT1 →	+0.695	+1.522	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,905 associations by consensus.

GNLY vs TYMP — GBM

Explore this scatter interactively →