GNLY

RNA expression — cross-omics
Cross-omicsRNA → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GNLY RNA expression is significantly associated with the RNA expression of many other genes, with 3,876 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GNLY-associated genes across cancer lineages are HSD17B6, ULK1, and HIF3A. Each is linked with GNLY in more than 3 cancer types. Because this analysis shows association rather than direction, both GNLY-to-partner and partner-to-GNLY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNLY versus HSD17B6 in LUNG_SCLC, with a Pearson correlation of 0.43.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNLY→partner) and Y-score (partner→GNLY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCHSD17B6 →+1.074+0.114.007.00333
STOMACHULK1 →+0.920+0.101<.001.00223
LUNG_SCLCHIF3A →+1.247+0.117.001<.00132
OVARYNTN5 →+0.404+0.103.008.00614
STOMACHYEATS2 →+0.971+0.173<.001.00123
BLOOD_LymphomaCD2 →+3.606+3.142<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,876 associations by consensus.

GNLY vs HSD17B6 — LUNG_SCLC

Per-sample scatter of GNLY vs HSD17B6 in LUNG_SCLC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration